OpenMFMPatient & family guide · September 2026
Opioid use disorder & pregnancy

Treatment can support you and your baby

A guide to medication, recovery, and caring for your newborn.

You deserve care.
You have treatment options.
You do not have to do this alone.

Sources [1], [2] • Slide 1 / 20
Your care journey

You can make a plan for every stage

Three things to understand before you leave today.

  1. 1

    Pregnancy

    Choose treatment that works for you.

  2. 2

    Birth

    Plan pain relief and newborn care.

  3. 3

    Recovery

    Keep support in place after delivery.

Sources [1], [2] • Slide 2 / 20
Understanding the words

Dependence and opioid use disorder are different

Knowing the difference can make treatment less confusing.

01

Physical dependence

Your body has adapted to an opioid. Stopping may cause withdrawal, even when you take medicine as prescribed.

02

Opioid use disorder (OUD)

A pattern of opioid use that causes harm or is hard to control. A clinician can help assess it.

Taking a prescribed opioid does not, by itself, mean you have OUD.
Sources [2], [3] • Slide 3 / 20
A safer next step

Talk with your team before stopping opioids

Wanting to protect your baby makes sense. Ask for a safe plan.

  1. 1

    Pause

    Avoid sudden changes on your own.

  2. 2

    Call your team

    Discuss withdrawal, cravings, and worries.

  3. 3

    Make a plan

    Medication treatment is usually preferred to withdrawal.

Return to use after stopping can lead to overdose, especially after your tolerance falls.
Sources [1], [3] • Slide 4 / 20
How treatment helps

Medicine helps control cravings and withdrawal

Methadone and buprenorphine are recommended treatments during pregnancy.

01

Medication

Helps you feel steady.

02

Prenatal care

Follows your health and pregnancy.

03

Support

Helps with stress and daily needs.

Taking treatment is a step toward recovery.
Sources [1], [2] • Slide 5 / 20
Choosing together

The right medicine fits your needs and your life

Your experience, preferences, and access to care matter.

01

Methadone

Treatment through a licensed opioid treatment program.

02

Buprenorphine

Treatment may be available through an office or clinic.

Staying well on your treatment matters. Do not switch medicines on your own.

Studies link buprenorphine with better average newborn outcomes. Much of that evidence is observational: it shows an association, not a guarantee for your baby.

Sources [3], [4] • Slide 6 / 20
Methadone

Methadone offers a structured treatment program

Your program works with you on medication and follow-up.

  1. 1

    Connect

    Find a licensed program.

  2. 2

    Plan visits

    Ask about visits and take-home options.

  3. 3

    Stay in touch

    Report symptoms and missed doses.

Store take-home medicine securely, away from children. Do not take an extra dose for a missed dose.
Sources [9], [10] • Slide 7 / 20
Buprenorphine

Buprenorphine can fit office-based care

A clinician plans how to start it safely and checks how you feel.

  1. 1

    Visit

    Discuss current opioids and past treatment.

  2. 2

    Start with guidance

    Timing matters to avoid sudden withdrawal.

  3. 3

    Follow up

    Review cravings and access to refills.

Ask which form is right for you. Do not start or switch on your own.
Sources [2], [3] • Slide 8 / 20
Staying steady

Report cravings so treatment can be adjusted

Pregnancy can change the amount or timing of medicine you need.

“I feel withdrawal or cravings before my next dose.”
Tell your team. A dose change can be part of good care.

Do not lower your dose to try to prevent newborn withdrawal.

Sources [3] • Slide 9 / 20
Another medicine

Naltrexone needs a separate discussion

Pregnancy safety information is more limited for naltrexone.

01

Already taking it?

Talk with your team before changing it. Staying stable and the risk of return to use both matter.

02

Considering starting it?

It is usually not the first choice in pregnancy. Ask a specialist about your options.

Sources [1], [3] • Slide 10 / 20
After your baby is born

Newborn withdrawal can be treated

Some babies exposed to opioids need observation and treatment after birth.

  1. 1

    Observe

    The team watches feeding, sleep, and other signs.

  2. 2

    Comfort

    Care starts with support for your baby.

  3. 3

    Treat as needed

    Some babies also need medicine.

This is called neonatal opioid withdrawal syndrome (NOWS), sometimes NAS. Withdrawal is not addiction, and it does not mean your treatment was a mistake.

Sources [2], [3] • Slide 11 / 20
Caring together

Your comfort and presence can help your baby

Ask how your hospital includes families in newborn care.

01

Eat

Feeding support helps your baby get enough nutrition.

02

Sleep

A calm, quiet space supports rest.

03

Console

Holding and skin-to-skin contact may help when safe.

Some teams use “Eat, Sleep, Console” to guide care. Medicine may still be needed.
Sources [5] • Slide 12 / 20
Your feeding plan

Breastfeeding is often possible during treatment

Methadone and buprenorphine taken under the tongue are generally compatible with breastfeeding.

01

Review together

Discuss all medicines, substances, and health conditions with your team.

02

Make a safety plan

Avoid breastfeeding during nonprescribed opioid use. Contact your team promptly for a safe feeding plan.

If your dose changes, ask what to watch for in your baby. Your team can support you with breastfeeding or another feeding choice.

Sources [6] • Slide 13 / 20
Your birth plan

You deserve effective pain relief during birth

Treatment medicine does not cover all labor or surgical pain.

Obstetric team
Anesthesia team
Treatment team
Plan additional pain relief before delivery. Continue your treatment medicine as directed.

Tell the hospital team what you take so they can coordinate safe pain care.

Sources [3] • Slide 14 / 20
Life after delivery

Recovery care continues after your baby is born

There is no fixed end date for treatment. Delivery is not a reason to stop.

01

Medicine

Arrange refills and your next visit.

02

Emotional support

Ask for help with mood, sleep, and stress.

03

Daily support

Plan help with rides, meals, and baby care.

Before discharge, know who to call if you need help.
Sources [1], [7] • Slide 15 / 20
Overdose emergency

Naloxone and a response plan can save a life

If someone will not wake up or is breathing slowly, act now.

  1. Call 911.Say the person may be overdosing.
  2. Give naloxone.Follow the product directions; more doses may be needed.
  3. Stay and help.Follow the dispatcher’s CPR or rescue-breathing instructions.
Do not withhold naloxone because of pregnancy. Show someone you trust where you keep it.
Sources [3], [8] • Slide 16 / 20
Getting help early

A return to use is a reason to seek help promptly

You deserve support at every stage of recovery.

“I missed doses or used again. I need help getting back to care.”
01

Call your team

Ask for help with cravings, missed doses, or return to use.

02

Name the barrier

Transport, housing, cost, or mood can affect care. Ask what support is available.

For an overdose emergency, call 911.

Sources [2], [9] • Slide 17 / 20
Take-home messages

Remember these five steps

Small plans can keep care connected.

  1. Stay connected to treatment.
  2. Discuss medication changes with your team.
  3. Prepare for your baby’s care.
  4. Plan follow-up after birth.
  5. Keep naloxone accessible.
Sources [1], [2], [8] • Slide 18 / 20
Bring these to your visit

Questions to Ask Your MFM Specialist

Your maternal-fetal medicine (MFM) specialist helps care for higher-risk pregnancies.

  • Which medicine fits my needs?
  • Who do I call for cravings or missed doses?
  • What is our birth and pain plan?
  • How will my baby be monitored?
  • Is breastfeeding appropriate for me?
  • Who coordinates care after discharge?

Use Print / PDF to keep this question list with the guide.

Sources [2], [3], [6] • Slide 19 / 20
Keep this guide

Reliable information can help you take the next step

Start with your care team, then use trusted resources.

This guide is for education and does not replace care from your own clinicians. For an overdose emergency, call 911.

Sources checked September 14, 2026. Full citations are in References and the printed appendix. This guide has no forms, trackers, or storage for personal health information.

Sources [1], [2] • Slide 20 / 20

References

Opioid Use Disorder and Pregnancy • OpenMFM • Sources checked September 14, 2026

  1. CDC. Treatment of Opioid Use Disorder Before, During, and After Pregnancy. May 1, 2026.https://www.cdc.gov/opioid-use-during-pregnancy/treatment/
  2. ACOG. Opioid Use Disorder and Pregnancy. Patient FAQ.https://www.acog.org/womens-health/faqs/opioid-use-disorder-and-pregnancy
  3. ACOG; ASAM. Opioid Use and Opioid Use Disorder in Pregnancy. Committee Opinion No. 711. Obstet Gynecol. 2017;130:e81–e94.https://www.acog.org/clinical/clinical-guidance/committee-opinion/articles/2017/08/opioid-use-and-opioid-use-disorder-in-pregnancy
  4. Suarez EA, Huybrechts KF, Straub L, et al. Buprenorphine versus Methadone for Opioid Use Disorder in Pregnancy. N Engl J Med. 2022;387:2033–2044. doi:10.1056/NEJMoa2203318.https://www.nejm.org/doi/10.1056/NEJMoa2203318
  5. Young LW, Ounpraseuth ST, Merhar SL, et al. Eat, Sleep, Console Approach or Usual Care for Neonatal Opioid Withdrawal. N Engl J Med. 2023;388:2326–2337. doi:10.1056/NEJMoa2214470.https://www.nejm.org/doi/full/10.1056/NEJMoa2214470
  6. Harris M, Schiff DM, Saia K, et al. Academy of Breastfeeding Medicine Clinical Protocol #21: Breastfeeding in the Setting of Substance Use and Substance Use Disorder (Revised 2023). Breastfeed Med. 2023;18:715–733. doi:10.1089/bfm.2023.29256.abm.https://www.bfmed.org/assets/DOCUMENTS/PROTOCOLS/21-drug-dependency-protocol-english.pdf
  7. Dowell D, Ragan KR, Jones CM, Baldwin GT, Chou R. CDC Clinical Practice Guideline for Prescribing Opioids for Pain — United States, 2022. MMWR Recomm Rep. 2022;71(RR-3):1–95. OUD treatment considerations.https://www.cdc.gov/mmwr/volumes/71/rr/rr7103a1.htm
  8. CDC. Lifesaving Naloxone. June 11, 2025.https://www.cdc.gov/stop-overdose/caring/naloxone.html
  9. SAMHSA. What Is Methadone? Treatment, pregnancy, and medication safety information.https://www.samhsa.gov/substance-use/treatment/options/methadone
  10. SAMHSA. 42 CFR Part 8 Final Rule: Frequently Asked Questions. Opioid treatment programs and take-home medication.https://www.samhsa.gov/substance-use/treatment/opioid-treatment-program/42-cfr-part-8/faqs

References

Guidance and research behind this patient guide. Sources checked September 14, 2026. A study describes groups of people; it cannot predict an individual outcome.

  1. CDC. Treatment of Opioid Use Disorder Before, During, and After Pregnancy. May 1, 2026.https://www.cdc.gov/opioid-use-during-pregnancy/treatment/
  2. ACOG. Opioid Use Disorder and Pregnancy. Patient FAQ.https://www.acog.org/womens-health/faqs/opioid-use-disorder-and-pregnancy
  3. ACOG; ASAM. Opioid Use and Opioid Use Disorder in Pregnancy. Committee Opinion No. 711. Obstet Gynecol. 2017;130:e81–e94.https://www.acog.org/clinical/clinical-guidance/committee-opinion/articles/2017/08/opioid-use-and-opioid-use-disorder-in-pregnancy
  4. Suarez EA, Huybrechts KF, Straub L, et al. Buprenorphine versus Methadone for Opioid Use Disorder in Pregnancy. N Engl J Med. 2022;387:2033–2044. doi:10.1056/NEJMoa2203318.https://www.nejm.org/doi/10.1056/NEJMoa2203318
  5. Young LW, Ounpraseuth ST, Merhar SL, et al. Eat, Sleep, Console Approach or Usual Care for Neonatal Opioid Withdrawal. N Engl J Med. 2023;388:2326–2337. doi:10.1056/NEJMoa2214470.https://www.nejm.org/doi/full/10.1056/NEJMoa2214470
  6. Harris M, Schiff DM, Saia K, et al. Academy of Breastfeeding Medicine Clinical Protocol #21: Breastfeeding in the Setting of Substance Use and Substance Use Disorder (Revised 2023). Breastfeed Med. 2023;18:715–733. doi:10.1089/bfm.2023.29256.abm.https://www.bfmed.org/assets/DOCUMENTS/PROTOCOLS/21-drug-dependency-protocol-english.pdf
  7. Dowell D, Ragan KR, Jones CM, Baldwin GT, Chou R. CDC Clinical Practice Guideline for Prescribing Opioids for Pain — United States, 2022. MMWR Recomm Rep. 2022;71(RR-3):1–95. OUD treatment considerations.https://www.cdc.gov/mmwr/volumes/71/rr/rr7103a1.htm
  8. CDC. Lifesaving Naloxone. June 11, 2025.https://www.cdc.gov/stop-overdose/caring/naloxone.html
  9. SAMHSA. What Is Methadone? Treatment, pregnancy, and medication safety information.https://www.samhsa.gov/substance-use/treatment/options/methadone
  10. SAMHSA. 42 CFR Part 8 Final Rule: Frequently Asked Questions. Opioid treatment programs and take-home medication.https://www.samhsa.gov/substance-use/treatment/opioid-treatment-program/42-cfr-part-8/faqs
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